Degenerative disc disease is characterized by dysfunction in which part of the spine?

Degenerative disc disease primarily involves the annular fibers of the intervertebral disc. This condition is marked by the wear and tear of the spinal discs, which serve as cushions between the vertebrae. The annulus fibrosus, which is the tough outer layer of the disc, can become weakened and may eventually lead to structural changes. Over time, this degeneration can result in pain, reduced mobility, and even issues like herniated discs, where the inner gel-like substance may protrude.

In this context, the dysfunction occurs specifically in the annular fibers because they are essential in maintaining the integrity and stability of the disc. As they deteriorate, the risk of further complications increases, which is why they play a central role in the understanding of degenerative disc disease.